Medico Guides 3rd Block Biochemistry Guidelines

Prepared by:

                            Ahsan Ali (G-14)

Compiled by:

                           Jawad Ashraf (G-14)

Reference Books:

• Lippincott Illustrated Reviews: Biochemistry 8^th Edition (Chapter numbers are mentioned according to this edition)
• Satya narayana Biochemistry 6^th Edition
• Harper’s illustrated Biochemistry 30^th edition

CARDIOVASCULAR SYSTEM

(Module No 04)

CV-B-001

• Classification of lipids (Satya chap 3)
• You must know one example
• Every classification

CV-B-002

• Biomedical importance & functions of lipids(imp) (Satya chap 3)

CV-B-003

• Fatty acids (Satya chap 3)
• Nomenclature of fatty acids + how to number carbon atoms (when starting from COOH     group, numbering is 1,2,3… when starting from terminal CH3 group, numbering is w1, w2, w3….) 
• Saturated and unsaturated fatty acids with examples (v.imp) w3, w6 and w9 fatty acids (also harper table 21.2) and also their functions (vv.imp)
• Essential fatty acids (functions, toad skin)
• Examples of hydroxy fatty acids + cyclic fatty acids(read)
• Trans fatty acids (adverse effects) (v.v.v.v.v.imp)
• Below topics are not your LO’s but still we got questions from them in block and prof!!!
• Functions of triacylglycerol (v.v.v.imp)
• Saponification (imp)
• Rancidity (imp) antioxidants examples (v.imp)
• Iodine number (v.imp)
• RM number 
• Saponification number (imp)
• Acid number
• Glycolipids (cerebrosides & gangliosides) (v.v.imp)
• Phospholipid classification with functions (v.imp)
• Structure of Phosphatidylcholine or Lecithin (v.imp)
• Functions of plasmalogens and Cardiolipin (v.v.v.imp)
• As a whole functions of phospholipids (v. imp)
• Lecithin-Sphingomyelin ratio = 2:1 after 30th week —-> Lung maturity Infant respiratory distress syndrome (v.v.v.imp)
• Amphipathic lipids
• Emulsion (read)liposome

CV-B-004

• Lipid peroxidation from the pics shared

CV-B-005

• Eicosanoids (Lippincott chap 17 Fig 17.23 only (v.v imp)
•  https://youtube/-JOn8g8LvwE?si=NvXQb_oGw1yhKp9w

CV-B-006

• Lipoprotein metabolism & disorders (Lippincott chap 18 pg # 252 to pg # 262+ fig imp)
• Regulations of cholesterol (fig 18.21) imp
• Foam cells (imp) HDL role (imp)

CV-B-007/CV-B-008

• Hyperlipidemias from pics & PDF shared

CV-B-009/CV-B-010

• Vitamins (Lippincott chap 28 complete)
• All vitamins are (v.v.v.v.v. imp)
• Vit.B9 and Vit.B12, folate trap, B12 absorption, VitA and VitD are much imp their clinical (deficiency and excess) also.

CV-B-011

• Minerals (Lippincott chap 29) https://youtube.com/playlist=PLk1F96oveZLGGviPzLJDxPCf1FURMT_NY&si=QTY3yYFHA3ldV7v6Zinc (imp)
• Magnesium, Sodium(imp), Potassium(imp), Calcium(v.v.imp), Iodide, Copper(v.imp). Phosphorus, Selenium(imp) & Sulphur
• Menkes syndrome+ Wilson disease (v.v imp)

RESPIRATORY SYSTEM

(Module No 05)

Re-B-001

• Single gene disorders (cystic fibrosis & emphysema) from PowerPoint slides shared
• Emphysema (lippon chp 4. Last 2page elastin and emphysema+ fig 4.14)

Re-B-002

• Diseases from your class lectures

Re-B-003

• Acid Base Balance (Satya chap 21 pg # 475 to pg # 485)
• This chapter is important for clinicals point of view
• 3 lines of defense (Blood buffer, Respiratory buffer, Renal buffer mechanisms) (imp)
• Metabolic acidosis, Respiratory acidosis, Metabolic alkalosis, Respiratory alkalosis their causes and compensatory mechanisms (v.v.v.v.v. imp)
• Tables 21.4 & 21.7 (v.v. imp)
• Anion gap + it’s significance (v.v.v.v.v.imp)
• Mixed acid base disorder (v.v.v.imp)