Prepared by:
Alisha Athar (G13)
Compiled by:
Rukhsar Uns (G14)
NEOPLASIA
Recommended Books:
- Robbins and Kumar Basic Pathology (Medium Robbins) Eleventh Edition
- Anwar General Pathology 2nd Edition
Chapter 5:
N-pa-001, 002:
- Definition of neoplasia
Neoplasia is defined as an abnormal mass of tissue which growth exceeds and is uncontrolled with that of the normal tissue and persist in the same excessive manner even after cessation of stimulus
- Nomenclature
- Learn definitions of benign and malignant tumor
- Benign Tumors (learn adenoma, papilloma, polyp, cystadenoma)
- Malignant Tumors (learn the point of carcinomas, hamartoma, choristoma)
- Table 6.1
- Characteristics of Benign and Malignant Neoplasms (definition of differentiation)
- Features of Anaplasia (four points)
- Definition of Local Invasion
- Definition of Metaplasia
- Pathways of Spread of Tumor (page 191 to 193)
- From epidemiology (Read Environmental Factors)
- Hallmarks Of Cancer (learn 8 points on pg 200)
- Self sufficiency in growth signals
- Growth Factors
- Growth Factor Receptors
- Page 203 (bold point for MCQ)
- Insensitivity to Growth Inhibitory Signals (Complete till page 208 along with Fig 6.18, 6.19, 6.20)
Tip: Read the theory and write all imp stuff on diagrams and just highlight points for MCQs
- Altered Cellular Metabolism (learn first three paragraphs)
- Evasion of Cell Death (from summary)
- Sustained Angiogenesis (from summary)
- Invasion and Metastasis (page 214 and 215)
- Fig 6.26, 6.27
- Rest of the hallmarks are sufficient from summary
Things to be done from Anwar:
- Difference between benign and Malignant Tumor
- Components of Tumor
- Carcinoma vs Sarcoma
- Exceptions in Nomenclature
- Cancer Genes (Read)
- Table 7.8, 7.9
N-pa-003:
- Carcinogenic agents on pg 220
- Learn Definitions of Direct and Indirect Agents
- Fig 6.31, 6.32
- Viral and Microbial Oncogenesis (Read and note viruses and cancers caused by them. You can also do it from Anwar)
N-pa-004:
- Lab diagnosis of Cancer on pg 227 (Names)
N-pa-005:
- Grading and staging of cancer on pg 227 (learn from Anwar as well)
- Tumor markers table from Big Robbins or from Anwar
N-pa-006:
- Already covered in above topics
N-pa-007:
- Paraneoplastic Syndromes on page 226 (learn definition and theory)
- Table 6.6