Medico Guides 6th Block Biochemistry Guidelines

by

Prepared by:

                  Nofal Anjum Khan (G13)

                  Aneesa Asif (G13)

Compiled by:

                  Talha Saleem (G12)

Reference Books:

  • Lippincott Illustrated Reviews: Biochemistry 8th Edition
  • Satyanarayana Biochemistry 6th Edition
  • Harper’s Illustrated Biochemistry 30th Edition
  • Chatterjee Biochemistry

DIGESTION AND ABSORPTION OF LIPIDS

Chapter 15:

NS-B-001

  • Digestion and absorption of lipids
  • Cystic fibrosis (imp)
  • Pancreatic enzymes fig 15.6 (imp)
  • Fig 15.2, 15.4, 15.6 & 15.7 (imp)
  • Role of Bile salts given in Section C “Emulsification in the small intestine”

CHOLESTEROL METABOLISM

Chapter 18:

NS-B-002a

  • Do this from Pg # 243 to Pg # 249 till cholesterol degradation
  • Whole topic is important
  • Fig 18.4 imp (Rate Limiting Reaction) important for SEQ and Viva
  • Fig 18.5 & 18.6 imp
  • Fig 18.7 vv.imp

LIPID METABOLISM

Chapter 16:

(Lipid Degradation)

NS-B-003

  • Do this from Pg # 209 to Pg # 216
  • Beta oxidation (imp for Seq and MCQs) with fig16.15 & 16.17
  • Do all of beta oxidation types with fig 16.20
  • Peroxisomal beta oxidation imp
  • Alpha oxidation (imp for MCQ)
  • Energy yield from palmitate fig 16.18

NS-B-004

  • Carnitine shuttle (vv imp) with fig 16.16
  • It’s inhibitor and source (imp for MCQ + Seq) and carnitine deficiency

(Lipid Synthesis)

NS-B-002b

  • Storage of fats Pg #208 & 209
  • “Storage as TAG components”

NS-B-005

  • Citrate shuttle fig 16.6 (imp)
  • Topic on Pg # 203 “Cytosolic Acetyl Co-A Production”

NS- B-006a

  • Do this from Pg # 203 to Pg # 209
  • Synthesis of fatty acid fig 16.9
  • Fig 16.7, 16.8   & 16.11 (imp)

NS-B-006b & NS-B-007a

  • Do this from Pg # 216 to Pg # 218
  • Fig 16.22, 16.23 & 16.24 (imp)
  • Fig 16.23 for SEQ (imp)

Chapter 17:

(Phospholipid Metabolism)

NS-B-007b

  • Do this from Pg # 224 to Pg # 230
  • Phospholipid structure is not a part of syllabus but it would be beneficial to do it as it makes easier to understand the metabolism
  • Fig 17.8 & 17.11 imp
  • Fig 17.10 for synthesis of sphingomyelin (imp)
  • Fig 17.11 degradation of phospholipid (imp)

(Glycolipids & Sphingolipids Metabolism)

NS-B-008

  • Do this from Pg # 230 to Pg # 235
  • Fig 17.18 & 17.19 imp

Chapter 24: (Lippincott)

NS-B-009

  • Fast feed cycle do all the figures and summary of this chap (this is not an imp chap) just do it briefly

Chapter 21:

NS-B-010

Topic: OTHER NITROGEN CONTAINING COMPOUNDS

NEOPLASIA

NS-B-011, NS- B-012, NS-B-013

  • Do table 37.2 37.3 and 37.4 from chapter 37 Satya
  • do the topic of oncogene, proto-oncogene and tumor markers from the same chap

NS-B-014

  • Chapter 31 from Satya
  • Give a thorough read to chapter

EICOSANOIDS

Chapter 17: (Lippincott)

IN-B-001

  • Fig 17.23, do each and everything (vv imp)
    • Eicosanoids synthesis and functions
    • Which enzyme is constitutive/inducible,
    • Names of COX inhibitors
    • Selective COX-2 inhibitor?
  • This fig is enough for your MCQs and SEQs but you can read last two pages of chapter to highlight important points.
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