Prepared by:
Christopher Stephen (G12)
Compiled by:
Hafiz Muhammad Umair Noor (G12)
Reference Books:
- Pathoma Fundamentals of Pathology
- Medium Robbins Latest Edition
- Essentials of Special Pathology by MBBS Cafeteria
Chapter 10:
Rheumatoid Arthritis:
- Mechanism(HLA association)
- Clinical features especially morning stiffness that improves with activity(often scenario is presented this way) and age (60+)
- Morphology from cafeteria book, in purple box
- Lab findings like antibodies and markers etc
- Treatment
Osteoarthritis:
- Mechanism (wear and tear)
- Presentation: age, stiffness that worsens during the day
- Morphology from cafeteria book
- Clinical features like osteophytes and nodes
- Treatment
Gout:
- Mechanism overproduction/underexcretion
- Types 1⁰ or 2⁰
- Clinical presentation
- Causes
- Lab findings (negative birefringence vvvvimp)
- Differentiate it from pseudogout (crystal shape and +ve birefringence)
Tumors:
- Scenario is asked, giant cell tumor and ewing sarcoma, osteosarcoma are more imp
- Focus on location, age bracket, any special finding(like soap bubble in giant cell), associations
- Tumor morphology from cafeteria book (super high yield)
- Soft tumors like lipoma etc
Note: You can use Robbins for morphologies if cafeteria is not suitable.