Medico Guides 1st Block (Module No 02) Biochemistry Guidelines

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Prepared by:

                     Muhammad Bilal Tariq (G15)

Compiled by:

                     Hafiz Muhammad Umair Noor (G12)

Reference Books:

  • Lippincott Illustrated Reviews: Biochemistry 8th Edition
  • Harper’s Illustrated Biochemistry 30th Edition
  • Satyanarayana Biochemistry 6th Edition

Haem Synthesis & Porphyria: (HL-B-001)

  • Do LO 1 & LO 2 From Lippin Ch#21
  • Fig 21.3, 21.4 21.5 & 21.8 are imp
  • Clinical application (Lead poisoning) Imp
  • Lecture for these LOs Brainless medicose

Globular Proteins: (HL-B-001) 

  • LO 3,4,5,6 & 7 All from lippin Ch#3
  • Do this whole chapter properly as it is imp
  • Fig 3.6 , 3.12 & 3.13 are imp
  • Lecture Medicosis perfectanalis or Rajesh Jambhulkar

Haemoglobinopathies: (HL-B-002)

  • Chap 3 Lippin
  • Pg # 37- 41 (all diseases are very important)
  • Among hemoglobinopathies: thalassemia, sickle cell anemia and methemoglobinemia are especially important. While doing disorders, never forget to do their mode of inheritance
  • Anemias same as physiology

Iron and Vitamins: (HL-B-003)

  • LO 1 Iron metabolism from lippin ch# 29 Pg # 450 &451 This table will also help you
  • LO 2 Iron deficiency anemia interpretation same as physiology
  • LO 3 Vit B9(folic acid) & Vit B12(Cobalamin) from lippin Ch#28
  • LO 4 Vit B6 (Pyridoxine) and Vit C&K from lippin Ch 28.
  • You should also know about the tests used for diagnosis of vitamins e.g High FiGlu in urine for folic acid deficiency and schilling test for Vit B12

Haem Degradation: (HL-B-004)

  • Heme Degradation from lippin Ch#21 Lippin
  • Fig 21.9 & 21.10 are imp along with theory

Jaundice/ Hyperbilirubinemia: (HL-B-005)

  • Do Hyperbilirubinemia / Jaundice & Types of Jaundice from Lippincott chap 21 pg # 316
  • Lecture for hyperbilirubinemia Dirty medicine
  • Difference between Types of Jaundice based on Lab Investigations
  • Lecture for Lab integration of jaundice Selfless medicos
  • Genetic basis of Jaundice, including:
  • Crigler Najjar Type 1
  • Crigler Najjar Type 2
  • Dubin-Johnson Syndrome
  • Gilbert Syndrome
  • Rotor Syndrome.        
  • This is the link for Dr Najeeb’s lecture which covers all the aspects of this LO. You can make your own lecture notes and get done with this topic for good. Also, this lecture is very extensive (a drawback of Dr Najeeb’s lecs) and there will be terms you may not be familiar with. You don’t need to get stuck with such nuances, just stay focused on your LOs.
  • Another option is osmosis videos which you can check for all the syndromes mentioned above.

Single Gene Defect: (HL-B-008)

  • Do Pedigree of single gene defects from the pictures given below:

Tip:  Always do mcqs given at the end of the chapter in lippincot…..Even if the full chapter isn’t included in your syllabus only do those mcqs related to your syllabus.

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