Medico Guides 5th Block (Module No 08) Biochemistry Guidelines

Prepared by:

                  Aneesa Asif (G13)

                  Nofal Anjum Khan (G13)

Compiled by:

                  Hafiz Muhammad Umair Noor (G12)

  • Lippincott Illustrated Reviews: Biochemistry 8th Edition (Chapter numbers are mentioned according to this edition)
  • Satyanarayana Biochemistry 6th Edition
  • Harper’s Illustrated Biochemistry 30th Edition
  • Mark’s Biochemistry 6th Edition
  • Lehninger Principles of Biochemistry 7th Edition
  • Lippincott Illustrated Reviews: Cell and Molecular Biology 2nd Edition

ENDOCRINE BIOCHEMISTRY

(EnR-B-001)

  • Do this from Guyton chp 75. By doing complete chapter u will cover these LOs.
  • Tables of chap 75 are v.v.v.imp

(EnR-B-002)

  • Do this from the pics/pdf shared

(EnR-B-003)

  • Do this from Satya chapter 19
  • You can also do it from Harper chapter 42 (pics are shared)

(EnR-B-004a)

  • Do this from pdf/pics shared

(EnR-B-004b)

  • Do this from Lippincott chapter 23
  • Insulin synthesis v.v.v.imp
  • Can also do from Guyton chapter 79

(EnR-B-004c)

  • Do this from Lippincott chapter 21(III-A) page no 317 to 319

(EnR-B-004d & 007)

  • Do these from Guyton chapter 76, 77 & 78
  • U can also do cortisol and other steroid hormones from Lippincott chapter 18 (VII) pg no 262 to 266

(EnR-B-005)

  • This is a general LO. It will be covered by doing other LOs.

(EnR-B-006)

  • Do this from Guyton chapter 78
  • Pro-opiomelanocortin gene topic complete

(EnR-B-008)

  • Do these from pics/pdf shared

GENETICS

(EnR-B-009 to 015)

  • Do these from the pics/pdfs shared

(EnR-B-016 to 017)

  • The topic of Karyotypes is not given in the book. Do it from pics shared.
  • As far as mutations are concerned, some of them are given in Lippincott chapter 32(II-C pg 498 & 499). Rest will be shared as pics.

(EnR-B-018 to 021)

  • No need to do the the structure of DNA as it is not the part of ur syllabus
  • Start from (III-Steps in ….) pg no 462 to 475
  • Although whole chapter is imp but the most important topics are below
  • Topoisomerases v.v.v.imp
  • Leading and Lagging strand imp
  • Exonuclease & Endonuclease imp
  • Fig 30.21, 30.23, 30.24 v.v.imp

(EnR-B-022)

  • DNA repair is an important topic u must do it all
  • Pg 475 to 477
  • Xeroderma pigmentosum v.v.imp

(EnR-B-023 to 025)

  • No need to do structure of RNA as not a part of syllabus
  • Start chapter from (III-Prokaryotic…) pg no 484 to 493
  • Again whole chapter is important but most important things are listed below
  • Fig 31.10 imp
  • Post-transcriptional changes v.v.v.imp

(EnR-B-026 to 028)

  • No need to do genetic codon as not in syllabus
  • Must do Mutations as part of previous LOs
  • The topic (III-Components Required For Translation) is not in ur syllabus but u should read it to understand the chapter. Rest is up to u.
  • Wobble hypothesis v.v.v.imp (IV-Codon Recog….)
  • Do chapter from pg 502 to 510
  • Most important things listed below
  • Shine-Delgarno Sequence imp
  • Fig 32.13, 32.14 imp
  • Co & Post-translational modifications v.v.v.imp

(EnR-B-029)

  • We did whole chapter in our 2nd yr as college faculty taught us so. They also assessed
  • But whole chapter is not in ur syllabus but still its a very important chapter
  • Do this chapter from pg 515 to pg 519 then pg 524 & 525
  • Lac operon v.v.v.imp (Fig 33.4 ratti honi chahiye)
  • Tryptophan operon imp
  • Iron metabolism & RNA interference v.v.imp
  • Rest chapter is up to you

(EnR-B-030)

  • Don’t do complete chapter as not in syllabus
  • Do DNA Cloning pg 534 to 537 (Fig 34.6)
  • Do DNA Sequencing from pg 539 (Fig 34.9 only)
  • Do Southern Blotting complete topic on pg 540. It will also cover Northern & Western Blotting. Also do Fig 34.25 imp
  • Do RFLP from pg 541 to 547
  • Do PCR from pg 547 to 550 v.v.v.imp topic (Was asked in Proff Written n Viva both)
  • Do Human Genome Project from Satya chapter 28

Chromosomal Abnormalities

Pedigrees & Karyotypes

Nuclear Receptor Mediated Signalling Pathway

Mutations (Mosaicism & Robertsonian Translocation)

Mendelian Inheritance Patterns

Hormonal Contraception Compresseds

GPCR Signalling Pathways

Features of Signal Transduction, Types of Hormones & Types of Receptors

Enzyme Linked Signalling Pathways

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