Medico Guides 3rd Block (Module No 05) Physiology Guidelines

Prepared by:

Khansa Noor (G15)

Compiled by:

Muhammad Ahmed Bhatti (G14)

Recommended Book:

Guyton and Hall Textbook of Medical Physiology 14^th Edition (Chapter numbers are mentioned according to this edition)

RESPIRATION

Note:

Watch medical gateway lectures and try to give read to guyton once to grasp concept

Chapter 38:

(Re-P-001 – 004)

Muscles involved in normal and laboured breathing (imp for viva and MCQs)
Pressure that causes movement of air in and out (i.e pleural pressure and alveolar pressure + transpulmonary pressure) Fig 38.2 vv imp
Compliance of lungs with fig 38.3 and 38.4 and factors (v.imp question for viva)
- Surfactant, surface tension & collapse of the alveoli and effect of thoracic cage (pg 499-500) not included
Work of breathing (blue box) imp
Pulmonary volumes and capacities with fig 38.6(whole topic v.v.v imp)
- Also do the table 38-1.
- Abbreviations and symbols + determination of functional… not included.
FEV1/FVC ratio clinical importance in obstructive and restrictive lung disease (v.v.v.imp viva/MCQs).
- You will read about this ratio in chapter 43 i.e decreases in obstructive diseases and increases/normal in restrictive diseases.
Minute respiratory volume and alveolar ventilation (imp for Viva)
Dead space and its types.
- From purple box, you only have to do anatomical vs physiological dead space + normal dead space volume value (150ml).
Rate of alveolar ventilation
Functions of respiratory passageways (purple box): from this you only have to do cough reflex and sneeze reflex (pg.506) (imp viva question).

Chapter 39:

(Re-P005 -006)

Physiological anatomy of pulmonary circulatory system + Pressures in pulmonary system (not imp, you can skip these topics).
Blood volume of lungs (MCQs)
Blood flow through lungs and its distribution (read)
- You can Skip from pg 510-511 or just give read (not imp).
- Do zones of pulmonary blood flow (imp for MCQs & viva) + factors that increase cardiac output.

Capillary dynamics (understand this topic for concept)
- Figure 39-6 + interrelations b/w interstitial fluid pressure and other pressure (Do these values as they can be asked in MCQs).
⁠Pulmonary edema (v.v.v.v.imp viva)
Fluid in pleural cavity (just read)
Pleural Effusion and causes (viva)

Chapter 40:

(Re-P 007)

(Skip from the start until 521)
Diffusion of gases through respiratory membrane (pg 521-524)
- Respiratory membrane + respiratory unit (imp)

(Re-P 011)

From purple box:
- Effect of ventilation perfusion ratio (imp)
- Below there to concept of physiological shunt ( just read for concepts, not imp)
- Concept of physiological shunt and physiological dead space (imp), you can skip the formulas given in this.
- Abnormalities of V/Q ratio (imp for MCQs)

Chapter 41:

(Re-P008-010)

Just do figure 41-3.

Role of hemoglobin in oxygen transport ( from pg. 530 till utilization coefficient.
Hemoglobin buffers tissue PO2 (pg 531-532) skip.
Bohr Effect with fig 41.10 and factors (pg 532-533) imp for MCQs and viva.
Metabolic use of oxygen: skip this topic.
Transport of oxygen in dissolved state blue box(mcq)
CO poisoning blue box with fig 41.12(viva)
Transport of CO2 with Fig 41.13 imp;

Chapter 42:

(Re-P016-018)

Chapter 43: (Most Important)

(Re-P019-030)

Note: Scenario type questions can be asked so do the diseases carefully.

Chapter 44:

(Re-P-013 – 014)

These terms are frequently asked in viva so do them properly