Medico Guides 3rd Block (Module No 04) Physiology Guidelines

Prepared by:

                            Asma Shafique (G15)                

Compiled by:

                            Muhammad Ahmed Bhatti (G14)

Recommended Book:

  • Guyton and Hall Textbook of Medical Physiology 14th Edition (Chapter numbers are mentioned according to this edition)

Reference Books:

  • Jaypee Essentials of Medical Physiology 6th Edition

Recommended lectures:

  • Medical gateway 
  • Byte sized med 

CARDIOVASCULAR SYSTEM

THE HEART

Chapter 9:

(CV-P-001 and 002)

  • Complete chapter.
  • Fig 9.5, 9.6, 9.7, 9.8(Imp)
  • Physiological anatomy of cardiac muscles 
  • Importance of intercalated disc 
  • Properties of cardiac muscles 
  • Phases of action potential of ventricle
  • Phases of action potential of SA node 
  • Mechanism of self excitation of SA node 
  • Refractory period with types and duration (from any short book)
  • Excitation contraction coupling mechanism 
  • Pressure and volume changes in left ventricle during cardiac cycle 
  • Cardiac cycle (most imp) complete (phases which are systole and diastole with events occurring in these phases)
  •  Relationship of cardiac cycle with ECG and heart sounds 
  • Atrial pressure waves in relation to cardiac cycle (in blue box)(imp for viva)
  • Aortic pressure curve (phases) with dicrotic notch or incisura (imp for viva) (from AI)
  • Definitions and normal values of cardiac output, stroke volume, end diastolic volume, and end systolic volume.
  • Frank starling mechanism( imp)
  • Autonomic regulation of heart 
  • Effect of calcium, potassium and temperature on heart 
  • Definitions of chronotropic, bromotropic, dromotropic, and ionotropic effects. (Given below)
  • Location of adrenergic and cholinergic receptors in heart  

(Adrenergic receptors are located in atria and ventricles 

Cholinergic receptors are found in atria, especially SA node)

  • Receptors present in coronary arterioles (adenosine receptors present in coronary arterioles, help in regulating blood flow)
  • Sympathetic and parasympathetic effects.

Chapter 10:

(CV-P- 003, Ectopic Pacemaker)

  • Read the chapter thoroughly and mark the mcq points.
  • fig 10.2 and 10.4
  • Conducting system of heart 
  • AV nodal delay with significance (imp)
  • Control of excitation and conduction in heart (ectopic pacemaker)
  • Why is the SA node considered the heart’s pacemaker?

Chapter 11:

(CV-P-004)

     (Read whole chapter for concept)

  • Normal ECG labelling, characteristics and time intervals

(vv imp for MCQs and Ospe as there is a separate station for ECG in Ospe)

  • Memorize name, placements and polarity of leads.
  • Einthoven’s law (v imp) and Einthoven’s triangle .

Chapter 12:

(CV-P-004)

  • Fig 12.2 and 12.3
  • Mean electrical axis.
  • Physiological basis of upright T wave in normal ECG 
  • Current of injury, including location and significance of J point (imp)
  • ECG changes in angina pectoris and myocardial infarction

(must do 4-5 changes )(imp)(from any short book or Al)

  • T wave abnormalities (v important)
  • Physiological and pathological causes of right and left deviation of axis of heart
  • Do the flowchart given below( can be done from AI)

Effect of electrolytes:

(CV-P-005)

Chapter 13

(CV-P-006)

  • Most important chapter.
  • Complete except paroxysmal tachycardia
  • AV block, ventricular fibrillation (v.v.imp)
  • Also compare fibrillation and flutter 
  • Should be able to recognize ECGs

(ECG changes are given and you have to identify the associated disorder

 from the given options)

CIRCULATION

Chapter 14, 15, 16:

(CV-P-007 and 008)

  • From Firdaus
  • Starling forces and Reynold’s number (with significance) are important
  • Functional parts of circulation 
  • Pressures in systemic and pulmonary circulation 
  • Types of Blood Flow 

Chapter 17:

(CV-P-009)

  • Complete (Guyton)

Chapter 18:

(CV-P-010 and 011)

  • From Guyton (v.imp)
  • Do all reflexes and make flow charts of them
  • Figure 18.10 (vv imp.)

Chapter 19:

(CV-P-012)

(You may read the whole chapter if you want,

 but only three topics are included in your LOs)

  • MEMORIZE three flowcharts: fig 19.6, fig 19.9, fig 19.12 (imp)

Chapter 20:

 (CV-P-013)

  • Normal values
  • Cardiac index
  • Hyper and hypo-effective heart 
  • Nervous control
  • Physiological and pathologically high and low CO.
  • Venous return (read and focus on headings)
  • Different methods for measuring cardiac output ( only names and fick’s oxygen method)

Chapter 21:

 (CV-P-014 and 015)

  • Regulation of skeletal muscle blood pressure 
  • Physiological anatomy of coronary circulation 
  • Regulation of coronary blood flow 
  • Angina pectoris, myocardial infarction and subendocardial infarction.

Chapter 23:

  • Heart sounds (v.v.v.imp) Table Given
  • Full chapter is v important
  • Should be able to recognize phonocardiograms.

Chapter 24:

  • Most important
  • Scenario based MCQS 
  • Do it complete from Guyton

Medico Guides 3rd Block (Module No 05) Physiology Guidelines

Prepared by:

                           Khansa Noor (G15)

Compiled by:

                            Muhammad Ahmed Bhatti (G14)

Recommended Book:

  • Guyton and Hall Textbook of Medical Physiology 14th Edition (Chapter numbers are mentioned according to this edition)

RESPIRATION

Note:

Chapter 38:

(Re-P-001 – 004)

  • Muscles involved in normal and laboured breathing (imp for viva and MCQs)
  • Pressure that causes movement of air in and out (i.e pleural pressure and alveolar pressure + transpulmonary pressure) Fig 38.2 vv imp
  • Compliance of lungs with fig 38.3 and 38.4 and factors (v.imp question for viva)
    • Surfactant, surface tension & collapse of the alveoli and effect of thoracic cage (pg 499-500) not included 
  • Work of breathing (blue box) imp 
  • Pulmonary volumes and capacities with fig 38.6(whole topic v.v.v imp)
    • Also do the table 38-1.
    • Abbreviations and symbols + determination of functional… not included. 
  • FEV1/FVC ratio clinical importance in obstructive and restrictive lung disease (v.v.v.imp viva/MCQs).
    • You will read about this ratio in chapter 43 i.e decreases in obstructive diseases and increases/normal in restrictive diseases.
  • Minute respiratory volume and alveolar ventilation (imp for Viva)
  • Dead space and its types.
    • From purple box, you only have to do anatomical vs physiological dead space + normal dead space volume value (150ml).
  • Rate of alveolar ventilation 
  • Functions of respiratory passageways (purple box): from this you only have to do cough reflex and sneeze reflex (pg.506) (imp viva question).

Chapter 39:

(Re-P005 -006)

  • Physiological anatomy of pulmonary circulatory system + Pressures in pulmonary system (not imp, you can skip these topics).
  • Blood volume of lungs (MCQs)
  • Blood flow through lungs and its distribution (read)
    • You can Skip from pg 510-511 or just give read (not imp).
    • Do zones of pulmonary blood flow (imp for MCQs & viva) + factors that increase cardiac output.
  • Capillary dynamics (understand this topic for concept)
    • Figure 39-6 + interrelations b/w interstitial fluid pressure and other pressure (Do these values as they can be asked in MCQs).
  • Pulmonary edema (v.v.v.v.imp viva)
  • Fluid in pleural cavity (just read)
  • Pleural Effusion and causes (viva) 

Chapter 40:

(Re-P 007)

  • (Skip from the start until 521)
  • Diffusion of gases through respiratory membrane (pg 521-524)
    • Respiratory membrane + respiratory unit (imp)

(Re-P 011)

  • From purple box:
    • Effect of ventilation perfusion ratio (imp) 
    • Below there to concept of physiological shunt ( just read for concepts, not imp)
    • Concept of physiological shunt and physiological dead space (imp), you can skip the formulas given in this.
    • Abnormalities of V/Q ratio (imp for MCQs)

Chapter 41: 

(Re-P008-010)

  • Skip from the start to role of hemoglobin in oxygen transport (pg.527-530).

Just do figure 41-3.

  • Role of hemoglobin in oxygen transport ( from pg. 530 till utilization coefficient.
  • Hemoglobin buffers tissue PO2 (pg 531-532) skip.
  • Bohr Effect with fig 41.10 and factors (pg 532-533) imp for MCQs and viva.
  • Metabolic use of oxygen: skip this topic.
  • Transport of oxygen in dissolved state blue box(mcq)
  • CO poisoning blue box with fig 41.12(viva)
  • Transport of CO2 with Fig 41.13 imp;
  1. Cl Shift/Hamburger phenomenon (vvimp)
  2. Carbon dioxide dissociation curve
  3. Haldane effect with Fig 41.15(imp) 
  • Respiratory Exchange Ratio (values are very imp for both MCQs and viva)

Chapter 42: 

(Re-P016-018)

  • ⁠Respiratory Centers (viva)
  • Inspiratory Ramp signal (iml)
  • Hering-Brerer reflex pg-540 (viva)
  • Chemical control (pg 541-545) imp 
  • Regulation of Respiration in exercise (imp)
  • Factors that affect reapiration + Chenye stroke Breathing(imp)  (blue box)
  • Sleep apnea (imp).

Chapter 43: (Most Important)

(Re-P019-030) 

Note: Scenario type questions can be asked so do the diseases carefully.

  • Skip from start and Do from Pathophysiology of specific pulmonary diseases (Risk factors, causes, management)
    • Pulmonary emphysema 
    • Pneumonia 
    • Atelectasis 
    • Asthma
    • Tuberculosis 
    • Cyanosis 
    • Dyspnea 
  • Hypoxia and oxygen therapy & hypercapnia (imp)

Chapter 44:

(Re-P-013 – 014)

  • Acclimatization 
  • Acute mountain sickness 
  • Chronic mountain sickness
  • Decompression sickness from Chapter 44 

Medico Guides 3rd Block Biochemistry Guidelines

Prepared by:

                           Warda Mehmood (G15)

Compiled by:

                            Muhammad Ahmed Bhatti (G14)

Reference Books:

  • Lippincott Illustrated Reviews: Biochemistry 8th Edition (Chapter numbers are mentioned according to this edition)
  • Satya narayana Biochemistry 6th Edition
  • Harper’s illustrated Biochemistry 30th edition 

CARDIOVASCULAR SYSTEM

(Module No 04)

Chapter: 3 (From Satya)

CV-B-001

  • Classification of lipids (V.important for both MCQs and Viva)
  • You must know the examples of each class and subclass and should be able to distinguish them in MCQs.

CV-B-002 

  • Biomedical importance & functions of lipids (Imp)

CV-B-003 

  • Fatty acids and its classification (V.imp from MCQs perspective) 
  • Nomenclature of fatty acids + how to number carbon atoms (when starting from COOH     group, numbering is 1,2,3… when starting from terminal CH3 group, numbering is w1, w2, w3….)  , examples of w3, w6, w9 fatty acids
  • Difference between w3 and w6 fatty acids (imp)
  • Classification on the basis of:
  • Even and odd number of carbons
  • Double bond :Saturated and Unsaturated fatty acids (Mono and Poly unsaturated) 
  • Omega carbon w3 and w6 (as explained above) also harpers table 21.2
  • Essential, Conditionally essential and Non essential fatty acids with examples (V.imp) , toad skin in deficiency of essential fatty acid (imp)
  • Cis and Trans fatty acids 
  • Cyclic fatty acids with example
  • Hydroxy fatty acid with example
  • Trans fatty acid with example and its harmful effects (V.imp)
  • Below topics are not in the LO’s but still we get lots of questions from them in both block as well as in proff
  • Functions of triacylglycerol (v.v.v.imp)
  • Saponification (imp) 
  • Rancidity (imp) antioxidants examples (v.imp)
  • Iodine number (v.imp) , represents degree of unsaturation , if more double bond present , then iodine number of fat/oil is high
  • RM number , soluble volatile fatty acids are higher in pure fat so if RM number is higher it means there is less adulteration of fat
  • Saponification number (imp) , tells about molecular size, small chain fatty acids have higher S.N
  • Acid number , if there is bacterial or chemical contamination, A.N is higher
  • Glycolipids (also called as glycosphingolipids) and its classes (cerebrosides & gangliosides) (v.v.imp)
  • Phospholipid classification (Glycerophospholipids and sphingophospholipids) complete with functions of each subclass  (v.imp)
  • Structure of Phosphatidylcholine or Lecithin (v.imp)
  • Functions of plasmalogens and Cardiolipin (v.v.v.imp)
  • As a whole functions of phospholipids (v. imp)
  • Lecithin-Sphingomyelin ratio = 2:1 after 30th week —-> Lung maturity Infant respiratory distress syndrome (v.v.v.imp)
  • Amphipathic lipids
  • Emulsion (read) liposome

CV-B-004 

  • Lipid peroxidation (v.v.v imp) , prepare it from the PDF shared 

Chapter: 17 (From Lippincott)

CV-B-005

  • Eicosanoids: Prostaglandins, Thromboxanes and Leukotrienes (Lippincott chap 17), also Fig 17.23 for functions only (v.v imp)
  • COX1 and COX2 difference (v.imp)
  • Anti-inflammatory agents (v.imp)
  • Difference between thromboxane A2 and prostacyclin (v.v.v imp)
  • Effect of Aspirin in Low dose aspirin therapy (imp)
  •  https://youtube/-JOn8g8LvwE?si=NvXQb_oGw1yhKp9w

 Chapter: 18 (From Lippincott)

CV-B-006 

  • Lipoprotein metabolism & disorders (pg # 252 to pg # 262), figures are very important for understanding , after doing from book go through that topic from the notes shared to get a stronger grip on your concepts.
  • Regulations of cholesterol (fig 18.21) imp
  • Foam cells (imp) HDL role (imp)

CV-B-007

  • Hyperlipidemias from pics & PDF shared 
  • This is a very important topic, questions are asked every time in Proff from this topic 
  • Must learn the symptoms, causes, names of each type, which type of lipid is higher in blood as scenario based questions are asked from this topic in Written and OSPE both

Chapter: 28 (From Lippincott)

CV-B-008/CV-B-009 

  • Vitamins (Lippincott chap 28 complete)
  • Classification from fig.28.1
  • All vitamins are (v.v.v.v.v. imp), do them completely from text and learn the names of their active forms too, however some important points I have mentioned below: 
  • Vit.B9, anemias and NTDs from its deficiency imp 
  •  Vit.B12, folate trap hypothesis (It explains how a vit B12 deficiency can lead to functional folate deficiency) , B12 absorption and pernicious anemia
  • Vit C , deficiency results in scurvy
  • VitB6 , use of drug isoniazid results in its deficiency 
  • Vit B1 , cofactor for which enzymes (learn), Cinical indications are v.v.v.v imp: Beri beri and its types ( 1.Adult: dry/neuritic&wet/oedematous + 2. infantile beri beri) ; Wernicke-Kosakoff syndrome (cerebral beri beri)
  • Vit B3 (treatment for hypelipidemias , deficiency)
  • VitB2
  • VitB7 
  • VitB5
  • Vit A ( complete as it is very very important), visual cycle, clinical indications, toxicity 
  • Vit D (v.v.v imp), metabolism, function, clinical indications 
  • Vit K in LO’s, it’s not mentioned but still have it’s understanding 
  • Vit E read once
  • Can revise the vitamins as a whole from fig.28.29 

Chapter: 29

CV-B-010

  • Mineral (completely learn)  https://youtube.com/playlist?list=PLk1F96oveZLGGviPzLJDxPCf1FURMT_NY&si=QTY3yYFHA3ldV7v6Zinc (imp)
  • Magnesium, Sodium(imp), Potassium(imp), Calcium(v.v.imp), Iodide, Copper(v.imp). Phosphorus, Selenium(imp) & Sulphur 
  • Menkes syndrome+ Wilson disease (v.v imp)
  • Iron (metabolism, deficiency and excess v.v.v imp)
  • Zinc (deficiency: acrodermatitis enteropathica 
  • Iodine (clinical indications v.imp)
  • Selenium v.imp (Keshan disease from Se-deficiency)
  • Memorize the names of the mineral requiring enzymes more importantly those written in text and then learn from the tables too given side by side.

RESPIRATORY SYSTEM

(Module No 05)

Re-B-001 

  • Single gene disorders (cystic fibrosis, emphysema, COPD and RDS) prepare this topic from medico express or any other short book.
  • Emphysema (Lippincott chp 4. Last 2page elastin and emphysema+ fig 4.14)

Chapter:21 (From Satya)

Re-B-002 to 010

  • Acid base balance complete from pg475 to 485 of this chapter to cover all your given LOs
  • This chapter is important for clinicals point of view
  • 3 lines of defense (Blood buffer, Respiratory buffer, Renal buffer mechanisms) (imp) 
  • Metabolic acidosis, Respiratory acidosis, Metabolic alkalosis, Respiratory alkalosis their causes and compensatory mechanisms (v.v.v.v.v. imp), will also be covered from the practical.Learn the normal values and you should be able to tackle the scenario based questions.
  • Tables 21.4 & 21.7 (v.v. imp)
  • Anion gap + it’s significance (v.v.v.v.v.imp)
  • Mixed acid base disorder (v.v.v.imp)

Medico Guides 3rd Block Embryology Guidelines

Prepared by:

                           Harram Sameer (G15)

                           Muhammad Bilal Tariq (G15)

Compiled by:

                           Muhammad Ahmed Bhatti (G14)

Reference Books:

  • Langman Medical Embryology 14th Edition
  • Make flow charts for all developments.
  • Don’t stick to every single line.

AXIAL SKELETON

Chapter 10

  • Do development of ribs and sternum given at the end of LANGMAN CH#10
  • Anomalies mentioned like cervical rib, Cleft sternum, pectus carinatum and excavatum (Imp)
  • Do development of vertebrae and vertebral column from LANGMAN  CH#10 
  • Anomalies are very imp for MCQs…

Chapter 7: 

  • Do development of Diaphragm and thoracic cavity from LANGMAN CH#7(Do it thoroughly till the end of chapter)
  • You must know about the Sources of diaphragm(4 sources)…You can listen to DR Azam’s lecture(It cover whole topic with clinical)
  • Must do anomalies Such as congenital diaphragmatic hernia etc….All are very imp and can be asked in both MCQs and VIVA as well…

CARDIOVASCULAR SYSTEM

Chapter 13:

CV-A-004 & CV-A-005:

  • For Early development of heart , do :
  • Establishment and patterning of primary heart field ( for mcqs)
  • Formation and positioning of heart tube 
  •  Formation of cardiac loop (vvvimp)
  • For Early Development of blood vessels, do:
  • Arterial and Venous System given under the topic of Vascular Development 
  • Development of Pericardial Cavity from any short book
  • For Parts of primitive heart tube and its folding , do the formation of cardiac loop
  • For Development of various chambers of heart and their partitioning , do :
  • Development of sinus venosus ( imp for mcqs)
  • Formation of cardiac septa  (vvimp)
  • Septum formation in common atrium (imp)
  • Formation of left atrium and pulmonary vein
  • Septum formation in Atrioventricular Canal 
  • Septum formation in truncus arteriosus and conus cordis (vimp)
  • Septum formation in ventricles (imp)
  • Identify parts of heart tube and structures derived from it ( imp for mcqs as well as ospe)

CV-A-006:

  • Dextrocardia and ectopia cordis given in clinical correlates (vvimp)
  • For Partitioning of primordial heart , Do septum formation in Common Atrium and septum formation in  Atrioventricular Canal 
  • Development of sinus venosus ( imp)
  • Atrial septal defects ( vvvimp)
  • Probe patent foramen ovale ( from any short book)
  • Partitioning of truncus arteriosus and bulbus cordis  (vvvimp)
  • Formation of ventricles and interventricular septum (imp)
  • Ventricular septal defects( vvvimp) 
  • Development of cardiac valves and conducting system
  • Development of Lymphatic System ( not imp, but you should have a concept of it)
  • Must do All the clinicals In between. 
  • Table 13.1 Not important (Just Go through for MCQs ) 
  • Table 13.2 (Important)

CV-A-007:

  • Developmental defects of heart : Tetralogy of fallot, patent ductus arteriosus, unequal division of arterial trunks, transposition of great vessels, valvular stenosis and coarctation of aorta ( vvimp)
  • Formation and fate of pharyngeal arch arteries given under the heading of Vascular Development, Table 13.3 ( Derivatives of Aortic Arch) is vvvimp . Vitelline, Umbilical and coronary Arteries are also important for MCQs 
  • Coarctation of Aorta and Anomalous Arteries (given under the clinical correlates of arterial System)
  • Clinicals of arterial System are very Important 

CV -A-008:

  • Development of embryonic veins : Vitelline, umbilical, common cardinal veins and their fate( given under the heading of venous system) 
  • Formation of superior & inferior Vena Cava and portal vein with their congenital anomalies (given under the heading of venous system) vvimp especially formation of Inferior Vena Cava and clinicals of venous system

CV-A-009: 

  • Derivatives of fetal vessels and structures from Langman chap 13 given under the heading of circulatory changes at birth (vvimp)
  • Fetal and neonatal circulation with transitional neonatal circulation and its clinical implications from Langman chap 13 under the heading of  Circulation before and after  birth, The five sites of mixing of blood are very important.

CV-A-010:

  • Atrial septal defects along with their embryological basis and features ( under the heading of heart defects) vvimp
  • Patent foramen ovale from any short book.
  • Developmental defects of heart : Tetralogy of fallot, persistent ductus arteriosus, unequal division of arterial trunks , transposition of great vessels and valvular stenosis (given in  clinical correlates) vvvimp

Most Important Clinicals:

  • Dextrocardia
  •  Ectopia cordis
  • Tetralogy of Fallot
  • Patent ductus arteriosus
  • Unequal division of arterial trunks
  • Transposition of great 
  • Vessels and Valvular stenosis
  • Coarctation of aorta
  • Ebstein Anomaly

RESPIRATORY SYSTEM

Chapter 14

  • LO#1 For this first read Formation of lung bud at the start of chapter Then understand thoroughly the Development of Larynx,Trachea and Bronchi..
  • LO#2 Do tracheoesophageal fistula from clinical correlates…Its types are written in description of pic must read those and Read VACTERL associations..(Vvvv Imp topic)
  • LO#3 For lung development and maturation first read from book then make a flowchart 
  • Also do Table 14.1 thoroughly…Must know the time frame and events of different phases
  • LO#4 Do all of these clinicals competely as they are Vvv imp…

Medico Guides 3rd Block Gross Anatomy Guidelines

Prepared by:

                            Harram Sameer (G15)

Compiled by:

                            Muhammad Ahmed Bhatti (G14)

Reference Books:

  • Snell’s Clinical Anatomy by Regions 10th edition
  • BD Chaurasia Human Anatomy 8th edition 

THORAX

Important Note:

  •  For thorax , you have to do chap 4&5 of Snell
  •  For clinicals use TH Clinicals but must give a good read to clinicals from Snell as many lines of Snell were asked as it is in our proff 
  • For mcqs practice use Chapter 1 & BRS gross anatomy (scenario MCQs) 
  • Nerve supply of diaphragm, structures passing through diaphragm, bronchopulmonary segment, root of lung , mediastinal syndrome it’s symptoms and effects (clinical v.v.imp). Guidelines are mentioned according to your LOs 

CARDIOVASCULAR SYSTEM

(Module No 4)

CV-A-001 

Mediastinum :

Lecture: Anatomy Zone ,Dr Hasna or Johri 

  • Definition, boundaries , compartments & contents of Mediastinum from BD chap 17  (complete) . Its schematic diagram is given below for your understanding:
  • Also do all the clinicals of Mediastinum from Snell or TH clinicals , Mediastinal syndrome is vvimp

Superior Vena Cava:

 Lecture: Taim Talks Med

  • Formation, Tributaries and Termination of Superior vena cava (imp) from BD chp 19  

Aorta:

 Lecture: Dr Hasna , TCML or About Medicine 

  • Formation , Branches and Distribution of Ascending Aorta, Aortic Arch and Descending Aorta in reference to their branches  from Snell chap 5  (imp)
  • Must Do relations of Aortic arch from BD chp 19 (also try to do relations of ascending and descending aorta but relations of aortic arch are most imp)

Azygous Vein : 

 Lecture: Essentials of Medical Sciences  or Taim Talks Med

  • Formation, course and tributaries of Azygous + Hemizygous + Accessory Hemizygous veins (extremely imp) from BD chp 14
  • Do it completely as they are frequently asked in exams (skip relations) 

Nerve supply of Heart : 

 Lecture: Dr Hasna , Kenhub , Dr Adel Bondok or Johri

  • Course , Relations and Distribution of Vagus Nerve and thoracic splanchnic nerves in relation to Nerve Supply of Heart from Snell chap 5 (under the topic extrinsic nerve supply)

CV-A-002

Pericardium:

      Lecture: Dr Azam 

  • Pericardium and its parts with emphasis on their nerve supply from Snell Chap 5 
  • Blood supply: Internal Thoracic Artery + Musculophrenic Artery + Descending Aorta 

Pericardial cavity and sinuses:

      Lecture : Dr Azam

  • Pericardial cavity ,  Transverse and oblique sinuses their Boundaries and clinical significance from BD chap 18 (v.v.imp)

Clinical Correlates:

  • Pericardial rub, pericardial pain , pericarditis, pericardial effusion, cardiac tamponade , paracentesis from Snell chap 5 

CV-A-003:

External Features of Heart:

      Lecture: Dr Azam

  • External features of heart , chambers of heart their features and openings  (just give a good read to this topic from Snell chp 5) They are mainly asked in Ospe and viva especially on model. So try to do its practice on heart model alongwith its diagram from Snell chap 5  and study all landmarks written in text 
  • Moderator Band is imp for written 

Arterial supply of Heart: 

      Lecture: Dr Azam

  • Coronary arteries (v.v.imp) complete from Snell chp 5 
  • Left and Right coronary artery branches + their  distribution + variations in coronary arteries+ sites of  anastomosis between right and left coronary artery + table 5.3 from Snell chap 5 (vvimp)
  • Anatomical correlates of cardiac Arterial supply from Snell chap 5

Clinical Correlates:

  • ECG , Cardiac referred pain , angioplasty and coronary grafts from Snell chap 5
  • Features of Angina Pectoris and MI from Snell chap 5 or TH clinicals

Venous Drainage of Heart:

      Lecture: Dr Azam

  • Venous drainage of heart & Alternative venous routes to heart from Snell chap 5 
  • Vessels supplying the heart with their origin and Termination from Snell chap 5

Cardiac plexus:

Lecture: Dr Hasna , Johri MBBS 

  • Formation, relations and distribution of Cardiac Plexus from BD chap 18 (imp)

Fibrous Skeleton & Cardiac Valves

  • Components and significance of Fibrous Skeleton of heart + valves from Snell chp 5 (imp)
  • Valvular Heart diseases from Snell chap 5
  • Surface marking, perform  percussion , auscultation and CT scan /MRI of heart and great vessels for OSPE

RESPIRATORY SYSTEM

(Module No 5)

Re-A-001

Thoracic Apertures:

 Lecture : Dr Hasna , Johri MBBS 

  • Superior thoracic aperture / Inlet of Thorax from BD chap 12
  • Inferior thoracic aperture ( also called as DIAPHRAGM) from Snell chap 4  (don’t skip any point and also do all clinicals) 
  • Do the table of openings and structures passing through these openings of diaphragm from BD chap 12 table 12.1 .Memorize  it completely as it is always asked either in written or in Viva (vvimp). Its pic is shared below:

Thoracic Outlet Syndrome:

  • Do it from Snell chap 4 (vvimp) 

Re-A-002 & Re-A-004:

Ribs:

Lecture: Dr Hasna , Johri or  Byte Sized Med 

  • Diff b/w typical and atypical rib (vvvvimp) from BD chap 13 or AI (While explaining the ribs in Ospe , you must know whether it’s typical or atypical rib)
  • Anatomical features of ribs from Snell chap 4 or BD chap 13 , Do 1st and 2nd ribs completely
  • Supernumerary cervical rib from Snell chap 4
  • Articulations of ribs are actually the joints . Do Classification of Articulations of ribs , Anatomical features of these Articulations and movements with Muscles producing articulations from BD chap 13 ( under the heading of joints of thorax) . You must also know the category of each rib ( vertebrosternal, vertebrochondral, typical, atypical etc )
  • Effects of fracture to neck of rib from Snell chap 4
  • Flail chest from Snell chap 4

Vertebra:

Lecture: Dr Hasna , Johri or Byte Sized Med 

  • Anatomical features of typical and atypical vertebrae and difference between them (vv imp) from BD chap 13 ( You should be able to differentiate between vertebrae in Ospe , For Ospe , you just have to do the bony features of vertebra)
  • Must know the difference of thoracic vertebrae from the other vertebrae 
  • Thoracic part of vertebral column ( normal curvature, intervertebral joints ) from BD chap 13 and do  fascia of back , blood supply, lymphatic drainage and nerve supply of back from any short book or AI
  • Kyphosis, Scoliosos  (vvimp) 

Re-A-003:

  • Thoracotomy (imp clinical) from Snell chap 4

Intercostal muscles:

  • Do intercostal muscles from Snell cha p 4 complete (imp)
  • Completely cover the headings of intercostal muscles + their actions+ nerve supply (main things asked are their actions , nerve supply and also their difference like direction of fibers etc) All this will be covered from Snell chap 4 , Also do table 4.1

Intercostal space :

    Lecture: Dr Azam

  • Intercostal space and its contents from  Snell chap 4 
  • In the topic of Intercostal space, 7 layers are written memorize these 7 layers in sequence and make mnemonic (v.v.imp mcq) 
  • Question is usually asked that if we have to perform lung biopsy, which layers will be pierced , the answer is these 7 layers
  • Contents of Intercostal space: Intercostal (Vein+ Artery+ Nerve) Mnemonic: VAN (imp)

Re-A-005 & Re-A-006:

Sternum:

Lecture: Dr Hasna , Johri MBBS

  • Do bony features of Sternum from Snell chap 4 or BD chap 13
  • Sternal biopsy , sternotomy and sternal fractures from Snell chap 4 or TH clinicals 

Endothoracic Fascia & Sibson’s fascia:

Lecture: Dr Azam

  • Endothoracic Fascia from Snell chp 4 
  • Suprapleural membrane (Sibson’s Fascia)  with attachments from Snell chap 4 ( imp)

Re-A-007 & Re-A-008: 

Joints of Thorax: 

Lecture: Taim Talks Med or Mina MedEase

  • Joints of Thorax from BD chap 13
  • For ligaments just do their names
  • You can revise the joints from the pic shared below:

Mechanics of Respiration:

 Lecture: Byte Sized Med 

  • Mechanics of Inspiration and Expiration from Snell chap 5 or BD 13 (vvvimp)
  • Vertical Diameter (Piston Pump Mechanism) from the pic shared below
  • Anteroposterior diameter (pump handle mechanism) , Transverse diameter (bucket handle mechanism) and  Vertical Diameter , All are vvimp
  • Muscles involved in respiratory movements from picture shared below

Intercostal Nerves and Vessels: 

      Lecture: Dr Azam

  • Origin, Course , Relation and Distribution of Intercostal Nerves from Snell chap 4
  • Origin , Course , Relation and Distribution of Intercostal Vessels (arteries and veins) from BD chap 14 (vvimp)
  • Posterior intercostal arteries from BD chap  14 
  • Anterior intercostal arteries from BD chap 14 
  • Intercostal veins from BD chap  14 complete (must do table 14.2 from BD) 
  • Alternate routes of Venous drainage in blockage of superior/ inferior Vena Cava  from Snell chap 5 , pic is shared below:

Re-A-009 & Re-A-010: 

Dermatomes :

  • Cutaneous Innervation and Dermatomes of Thorax from any short book or AI (not imp)

Diagram of cutaneous innervation is given below:

Clinical Correlates: 

  • Herpes Zoster Infection on thoracic wall and Intercostal Nerve block from Snell chap 4

Trachea:

  • Anatomical features, extent , relations, neurovascular supply and lymphatics of trachea from Snell chap 5

Re-A-011:

Diaphragm:

  Lecture : Dr Hasna , Johri MBBS

  • Parts of Diaphragm, their attachments and neurovascular supply from Snell chap 4
  • Role of Diaphragm in Respiration from Snell chap 4
  • Diaphragmatic apertures from BD table 12.1 (vvimp)

Re-A-012:

Pleura:

Lecture: Dr Azam

  • Parts, Layers , neurovascular supply  of pleura from Snell chap 5 (vvimp)
  •  Blood supply and Lymphatic drainage from picture shared below:
  • Difference between parietal and visceral pleura from BD chap 15  table 15.1 :

Pleural cavity:

  • Pleural cavity, its recesses and lines of reflection from Snell chap 5 ( under the heading of pleura)
  • Pleural reflections ( clinical) from Snell chap 4

Clinical Correlates:

  • Pleural pain , pleurisy, pneumothorax, pleural effusion from Snell chap 5 

Lungs:

 Lecture: Dr Azam 

  • Anatomical features and relations of lungs from Snell chap 5
  • Lobes and Fissures of lungs from Snell chap 5  +  table 5.1 v.imp. 

Re-A-013:

Lungs:

     Lecture: Dr Azam

  • Neurovascular supply and Lymphatic drainage of lungs from Snell chap 5
  • Difference between Anatomical features of right and left lung from BD table 16.2: 

Root of lung:

 Lecture: Dr Azam

  • Pulmonary Ligament (covered in topic of Pleura from Snell chap 5) 
  • Root of lung from BD chap 16  (vvvimp)
  • In root of lung cover following headings from BD: Contents+ arrangement of structures in root+ Relations of root 

Bronchopulmonary Segments:

Lecture: Dr Azam

  • Bronchopulmonary segments complete (extremely imp) from Snell chap 5 (don’t skip anything) , Also do its diagram from the pic shared below:
  • Blood supply, Nerve Supply, Lymphatic drainage and clinical significance of bronchopulmonary segments from Snell chap 5

Clinical Correlates:

  • Chest tube intubation, Thoracentesis, bronchoscopy from Snell chap 5 or TH clinicals
  • Anatomical basis for medicolegal significance of lungs in determining viability of new born from any short book or AI
  • Anatomical landmarks on chest X-rays, CT , MRI for Ospe 

Note

Medico Guides 3rd Block Histology Guidelines

Prepared by:

                           Hadia Shakeel (G15)

Compiled by:

                           Muhammad Ahmed Bhatti (G14)

Reference Books:

  • Medical Histology by Laiq Hussain 8th edition (Chapter numbers are mentioned according to this edition)
  • Manual of Histology (your practical notebook)

CARDIOVASCULAR SYSTEM

(Module No 4)

Chapter 13:

  • CVA-011 – CVA-017
  • Endocardium, Myocardium & Epicardium (Cover all these layers properly…the most important in this regard is the Myocardium as it contains the arrangement of muscle fibers in the atria and ventricles)
  • Complete topic of cardiac skeleton…The paragraph under the heading of impulse generating and conducting system of the heart is especially imp because it contains the location of SA node AV node etc…moreover it also contains some of the distinguishing features of the cardiac muscle cells found in SA node…also Cover Purkinje Fibres
  • You people have already covered cardiac muscle in block 2…revise the topic from the chp of muscles.
  • Endothelium & its Functions IMP
  • Layers of blood vessels i.e. tunica intima, media & adventitia
  • The Difference between Different Arteries, Different Veins & Capillaries can be done from your Histo Practical Notebook or You can do it Thoroughly by understanding Diagrams Along with their histological Features (Very Important to Do) 
  • The differences between veins and arteries can be covered in the tabulated form from any short book
  • All green Boxes Diseases are a Must Do thing, never skip these i.e Thrombosis & Embolism, lymphedema, Blood pressure Diseases Arteriosclerosis, Atherosclerosis Important
  • Pericytes Important
  • Difference between capillaries types, their Examples …very very important
  • Vein Types must do their Difference
  • Thoroughly cover the topic of lymph vascular system…the paragraph of lymph capillaries contains the differences of lymphatic capillaries from the blood capillaries so do it properly….otherwise the entire topic is supposed to be covered

RESPIRATORY SYSTEM

(Module No 5)

Chapter 17: 

  • Re-A-019 – Re-A-024
  • Proximal / Distal Respiratory Tract 
  • Respiratory epithelium Complete, Cell Names and Description Important 
  • Olfactory epithelium, Cell Names and Description Important
  • The most imp thing in this chp is the epithelial changes from the start of Respiratory Tract to the very end of the tract. You will be asked mcqs related to these changes.
  • Paranasal sinuses, Nasopharynx, Larynx Do Their layers with Complete description
  • Trachea Important Diagram and Layers Both are very important 
  • Also cover the bronchial tree
  • Difference b/w intra and extra pulmonary bronchi Important 
  • Also cover bronchioles
  • Terminal Bronchioles & Clara cells (Club cells) Very Important  
  • Since in your syllabus the topic of lungs is mentioned so you are supposed to cover all the headings under the main heading of lungs…whether these are separately mentioned in your Los or not.
  • Diff between type 1 and 2 Pneumocytes and their imp features…both are important 
  • Pulmonary Surfactant, Dust cells and Blood Air Barrier Very Important
  • Epithelium of Bronchioles to Alveolar sacs is Repeatedly Asked. Must remember it 
  • All green boxes are Important to do. Don’t skip these boxes

Medico Guides 3rd Block Minors Guidelines

Prepared by:

                           Hadia Shakeel (G15)

Compiled by

                     Muhammad Ahmed Bhatti (G14)

PATHOLOGY

(Module No 04)

  • CV001 – CV007:
  • Cover the entire topic of Inflammation from Chp1
  • Thrombosis, embolism, and infarction from Chp1 
  • The entire topic of hypertension from Medicnetic
  • Shock…from Chp1
  • Cover heart failure from Chp1 …additionally cover Congestive heart failure from medicnetic
  • Also cover Ischemic heart diseases and cardiac output from Chp1

PHARMACOLOGY

C.MED

  • CM-001 – CM-007:
  • For CVS Module the content of C.med is well explained in Chp1 So cover it from there 
  • Additionally cover primordial prevention, health promotion, secondary and tertiary prevention and behavioral change interventions from medicnetic and you are good to go with C.Med.

BEHAVIORAL SCIENCES

  • Bh-S001 – Bh-S002:
  • Psychosocial aspects from Medicnetic 
  • Emotional fainting from Chp1

PATHOLOGY

(Module No 05)

  • LO-1:   
  • Acute respiratory distress syndrome is very well written in medicnetic so do cover it from there.
  • LO-2: 
  • Obstructive and restrictive lung diseases…cover the topic from Chp1.
  • LO-3:
  • Differences between Obstructive and restrictive lung diseases are also mentioned in Chp1 So cover it from there.

PHARMACOLOGY

C.MED

  • CM-001 – CM-004:
  • Cover risk factors and preventive strategies from Chp1
  • Common vaccines used for the prevention of ARI are well written in medicnetic so do cover them from that book.
  • You people are supposed to cover the role of vitamins from both…medicnetic as well as the Chp1.
  • The effect of air pollutants will be covered from Chp1 under the heading of Environmental interaction and respiratory system.
  • Cover epidemiology of Respiratory diseases and occupational lung diseases from Chp 1

BEHAVIORAL SCIENCES

  • BhS-001 – BhS-003:
  • Topic of Dyspnea from Medicnetic
  • Cover psychogenic cough from both…Chp1 and medicnetic
  • Psychosocial aspects to be covered from the medicnetic.